Lisa M Guay-Woodford Selected Research

Autosomal Recessive Polycystic Kidney (Polycystic Kidney Disease, Infantile, Type I)

12/2018	Polycystic kidney disease.
10/2017	NEDD4-family E3 ligase dysfunction due to PKHD1/Pkhd1 defects suggests a mechanistic model for ARPKD pathobiology.
1/2017	Design and Implementation of the Hepatorenal Fibrocystic Disease Core Center Clinical Database: A Centralized Resource for Characterizing Autosomal Recessive Polycystic Kidney Disease and Other Hepatorenal Fibrocystic Diseases.
8/2015	Magnetic resonance microscopy of renal and biliary abnormalities in excised tissues from a mouse model of autosomal recessive polycystic kidney disease.
10/2014	Neurocognition in children with autosomal recessive polycystic kidney disease in the CKiD cohort study.
9/2014	Autosomal recessive polycystic kidney disease: a hepatorenal fibrocystic disorder with pleiotropic effects.
1/2014	Autosomal recessive polycystic kidney disease: the prototype of the hepato-renal fibrocystic diseases.
1/2013	The ciliary protein cystin forms a regulatory complex with necdin to modulate Myc expression.
12/2009	Cystin localizes to primary cilia via membrane microdomains and a targeting motif.
6/2006	Loss of primary cilia results in deregulated and unabated apical calcium entry in ARPKD collecting duct cells.

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Lisa M Guay-Woodford Research Topics

Disease

15	Autosomal Recessive Polycystic Kidney (Polycystic Kidney Disease, Infantile, Type I) 12/2018 - 04/2000
11	Autosomal Dominant Polycystic Kidney (ADPKD) 12/2018 - 04/2002
8	Cysts 01/2007 - 04/2000
7	Polycystic Kidney Diseases (Polycystic Kidney Disease) 06/2011 - 02/2002
5	Hypertension (High Blood Pressure) 10/2017 - 02/2003
3	Disease Progression 12/2018 - 04/2006
1	Neoplasms (Cancer) 01/2021
1	Membranous Glomerulonephritis (Membranous Nephropathy) 01/2019
1	Lipoid Nephrosis (Glomerulonephritis, Minimal Change) 01/2019
1	IGA Glomerulonephritis (IGA Nephropathy) 01/2019
1	Focal Segmental Glomerulosclerosis (Glomerulosclerosis, Focal) 01/2019
1	Chronic Kidney Failure (Chronic Renal Failure) 01/2019
1	Fibrosis (Cirrhosis) 10/2017
1	Kidney Diseases (Kidney Disease) 06/2015
1	Proteinuria 06/2015
1	Ciliopathies 10/2010
1	Colonic Neoplasms (Colon Cancer) 10/2010
1	diffuse Mesangial sclerosis 07/2010
1	Nephrotic Syndrome (Syndrome, Nephrotic) 07/2010
1	Azotemia 05/2006
1	Renal Insufficiency (Renal Failure) 12/2003

Drug/Important Bio-Agent (IBA)

12	Proteins (Proteins, Gene)FDA Link 12/2018 - 02/2002
4	Iothalamic Acid (Iotalamic Acid)FDA Link 01/2007 - 09/2003
3	Biomarkers (Surrogate Marker)IBA 01/2019 - 12/2003
3	CreatinineIBA 03/2006 - 09/2003
2	Biological ProductsIBA 01/2019 - 12/2018
2	SodiumIBA 10/2017 - 01/2007
2	Antihypertensive Agents (Antihypertensives)IBA 10/2014 - 02/2003
2	AlbuminsIBA 01/2007 - 09/2003
1	necdinIBA 01/2021
1	Immunoglobulin A (IgA)IBA 01/2019
1	Sirolimus (Rapamycin)FDA Link 12/2018
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 12/2018
1	Ubiquitin-Protein Ligases (Ubiquitin-Protein Ligase)IBA 10/2017
1	Biocompatible Materials (Biomaterials)IBA 01/2017
1	Apolipoprotein L1IBA 06/2015
1	Dexamethasone (Maxidex)FDA LinkGeneric 06/2015
1	Mycophenolic Acid (Cellcept)FDA LinkGeneric 06/2015
1	Cyclosporine (Ciclosporin)FDA LinkGeneric 06/2015
1	Hepatocyte Nuclear Factor 6IBA 06/2011
1	3- (3,5- dichlorophenyl)- 1- methyl- 2,5- pyrrolidinedione (DPMS)IBA 06/2011
1	Retinaldehyde (Retinal)IBA 10/2010
1	AntigensIBA 10/2010
1	phospholipase C epsilonIBA 07/2010
1	AcidsIBA 12/2009
1	GadoliniumIBA 04/2009
1	Uric Acid (Urate)IBA 01/2007
1	LDL CholesterolIBA 01/2007
1	A-factor (Streptomyces)IBA 06/2006
1	CalciumIBA 06/2006
1	KinesinsIBA 04/2005
1	ElectrolytesIBA 09/2003
1	Immunoglobulins (Immunoglobulin)IBA 05/2002
1	Transcription Factors (Transcription Factor)IBA 05/2002
1	plexinIBA 05/2002
1	Adenosine Triphosphate (ATP)IBA 04/2002
1	LectinsIBA 04/2000

Therapy/Procedure

5	Therapeutics 01/2019 - 12/2003
1	Euthanasia (Mercy Killing) 08/2015